Globally incidence of Non Hodgkin’s lymphoma (NHL) is 3% of which 1% occurs in extranodal lymphoma [1]. Among them, diffuse large B-cell lymphoma (DLBCL) is the most common subtype, accounting for 50% of the cases [2]. Plasmablastic lymphoma (PBL) is a rare and aggressive variant of DLBCL with plasmablastic features, commonly occurs in the oral cavity of human immunodeficiency virus (HIV) infected patients. Primary female genital system lymphoma (PFGSL) is a rare disease, accounting for 0.21-1.1% of extranodal lymphoma [2,3]. Here we report a unique rare case of Uterine PBL in an HIV/Epstein-Barr virus-negative patient that was initially diagnosed as endometroid carcinoma.
