The Journal of Obstetrics and Gynaecology of India
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VOL. 72 NUMBER 6 November-December  2022

Peripheral Gangrene, a Rare Side Effect of Methergine, Secondary to Antiphospholipid Antibody Syndrome: Case Report

Major Anjali Rani Preeti Vashistha Mayank Sharma Amrita Singh

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Background

Ergot derivatives are commonly used for the treatment of postpartum as well as postabortal hemorrhage. Peripheral Gangrene is a rare acute complication of administration of ergometrine and its analogue in patients with postpartum or postabortal hemorrahge

Case report

We report a case of 25 years multipara with undiagnosed primary antiphospholipid antibody syndrome, develops fingertip gangrene after the use of Inj Methergine to manage postabortal hemorrage.

Conclusion

Methergine use always needs a word of caution, before its use we have to rule out all the contraindications and assess high risk patients who have high chances of complications.

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