The Journal of Obstetrics and Gynaecology of India
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:: Article: Centchroman - A novel drug for D U B
:: Author(s): Sudha Prasad
:: Keyword : Centchroman - A novel drug for D U B

:: SUMMARY : : Prospective study of 70 cases of DUB diagnosed after following certain exclusion criteria were recruited. Abnormal endometrial pattern was excluded in perimenopausal patients. All the patients were followed-up on tablet Centchroman 30mg. bi-weekly for 6 months. Eighty percent of patients were relieved of menorrhagia at the end of the treatment. Majority of patients (90%) reverted to their normal cycle by 4th month. The incidence of amenorrhoea and oligomenoiThoea were observed in 4.2% and 5.7% of patients respectively. No abnormal effect was seen on endometrium after the treatment. Side effects were few and were well tolerated by the patients. Centchroman was found to be very effective in controlling the symptoms Of D U B.

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